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Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2409f0f6f05e4b0d801cc71746493996

Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

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Scope and Contents

Contents

The major cause of death after allogeneic Hematopoietic Stem Cell Transplantation (HSCT) for acute myeloid leukemia (AML) is disease relapse. We investigated the expression of Inhibitory Receptors (IR; PD-1/CTLA-4/TIM-3/LAG-3/2B4/KLRG1/GITR) on T cells infiltrating the bone marrow (BM) of 32 AML patients relapsing (median 251 days) or maintaining c...

Alternative Titles

Full title

Bone marrow central memory and memory stem T-cell exhaustion in AML patients relapsing after HSCT

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Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2409f0f6f05e4b0d801cc71746493996

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2409f0f6f05e4b0d801cc71746493996

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-08871-1

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