Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtai...
Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by vasculopathy and progressive fibrosis of skin and several internal organs, including lungs. Macrophages are the main cells involved in the immune-inflammatory damage of skin and lungs, and alternatively activated (M2) macrophages seem to have a profibrotic role thr...
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Full title
Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease
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TN_cdi_doaj_primary_oai_doaj_org_article_2410ffffdc874c1c8aaea19047f0e08f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2410ffffdc874c1c8aaea19047f0e08f
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ISSN
1478-6362,1478-6354
E-ISSN
1478-6362
DOI
10.1186/s13075-024-03308-7
