Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target...
Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Immunotherapies with antibody-drug-conjugates (ADC) and CAR-T cells, targeted at tumor surface antigens (surfaceome), currently revolutionize clinical oncology. However, target identification warrants a better understanding of the surfaceome and how it is modulated by the tumor microenvironment. Here, we decode the surfaceome and endocytome and its...
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Full title
Decoding of the surfaceome and endocytome in primary glioblastoma cells identifies potential target antigens in the hypoxic tumor niche
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TN_cdi_doaj_primary_oai_doaj_org_article_2420e036341048829943fa3b910fe88d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2420e036341048829943fa3b910fe88d
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ISSN
2051-5960
E-ISSN
2051-5960
DOI
10.1186/s40478-024-01740-z
