PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor
PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The Published Kinase Inhibitor Set (PKIS) is a publicly-available chemogenomic library distributed to more than 300 laboratories by GlaxoSmithKline (GSK) between 2011 and 2015 and by SGC-UNC from 2015 to 2017. Screening this library of well-annotated, published kinase inhibitors has yielded a plethora of data in diverse therapeutic and scientific a...
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PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor
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TN_cdi_doaj_primary_oai_doaj_org_article_2427271ceabc4a4d9e480023fca08c5f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2427271ceabc4a4d9e480023fca08c5f
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-72869-9
