Mechanism of oxymatrine in the treatment of cryptosporidiosis through TNF/NF-κB signaling pathway ba...
Mechanism of oxymatrine in the treatment of cryptosporidiosis through TNF/NF-κB signaling pathway based on network pharmacology and experimental validation
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Author / Creator
Zhang, Xiaoning , Shi, Jie , Lu, Yilong , Ji, Rui , Guan, Zhiyu , Peng, Fujun , Zhao, Chunzhen , Gao, Wei and Gao, Feng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Contents
Cryptosporidiosis is a worldwide zoonotic disease. Oxymatrine, an alkaloid extracted and isolated from the plant bitter ginseng, has been reported to have therapeutic effects on cryptosporidiosis. However, the underlying mechanism of its action remains unclear. In this study, we utilized network pharmacology and experimental validation to investiga...
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Full title
Mechanism of oxymatrine in the treatment of cryptosporidiosis through TNF/NF-κB signaling pathway based on network pharmacology and experimental validation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_243f01f7e8dc48ae88dcb998f6896ff2
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_243f01f7e8dc48ae88dcb998f6896ff2
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-65362-0
