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scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies

scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_244a1e2437984f2681930cdb0b3790c0

scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies

About this item

Full title

scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-11, Vol.12 (1), p.6625-18, Article 6625

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Single cell RNA-seq has revolutionized transcriptomics by providing cell type resolution for differential gene expression and expression quantitative trait loci (eQTL) analyses. However, efficient power analysis methods for single cell data and inter-individual comparisons are lacking. Here, we present scPower; a statistical framework for the desig...

Alternative Titles

Full title

scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_244a1e2437984f2681930cdb0b3790c0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_244a1e2437984f2681930cdb0b3790c0

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-26779-7

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