Direct comparison of distinct naive pluripotent states in human embryonic stem cells
Direct comparison of distinct naive pluripotent states in human embryonic stem cells
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Author / Creator
Warrier, S. , Van der Jeught, M. , Duggal, G. , Tilleman, L. , Sutherland, E. , Taelman, J. , Popovic, M. , Lierman, S. , Chuva De Sousa Lopes, S. , Van Soom, A. , Peelman, L. , Van Nieuwerburgh, F. , De Coninck, D. I. M. , Menten, B. , Mestdagh, P. , Van de Sompele, J. , Deforce, D. , De Sutter, P. and Heindryckx, B.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Until recently, human embryonic stem cells (hESCs) were shown to exist in a state of primed pluripotency, while mouse embryonic stem cells (mESCs) display a naive or primed pluripotent state. Here we show the rapid conversion of in-house-derived primed hESCs on mouse embryonic feeder layer (MEF) to a naive state within 5–6 days in naive conversion...
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Full title
Direct comparison of distinct naive pluripotent states in human embryonic stem cells
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_244cbf649add464c82660353beddd982
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_244cbf649add464c82660353beddd982
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15055
