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PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification

PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2464bcbe49344c5183fb66578cc151b9

PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification

About this item

Full title

PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification

Publisher

England: BioMed Central

Journal title

BMC biology, 2025-02, Vol.23 (1), p.64-12, Article 64

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Peroxisome proliferator-activated receptor α (PPARα) plays a crucial role in liver physiological and pathological processes. Yes-associated protein (YAP) is a key effector in regulating cell growth and organ size. Ubiquitination is known to modulate YAP protein expression, stability, and nuclear localization. Our previous study demonstrated that PP...

Alternative Titles

Full title

PPARα regulates YAP protein levels and activity by affecting its ubiquitination modification

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2464bcbe49344c5183fb66578cc151b9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2464bcbe49344c5183fb66578cc151b9

Other Identifiers

ISSN

1741-7007

E-ISSN

1741-7007

DOI

10.1186/s12915-025-02163-5

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