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Cellular senescence mediates fibrotic pulmonary disease

Cellular senescence mediates fibrotic pulmonary disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_24b84bad3904485caad4533a2d6fd946

Cellular senescence mediates fibrotic pulmonary disease

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Publication information

Publisher

London: Nature Publishing Group UK

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Scope and Contents

Contents

Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by interstitial remodelling, leading to compromised lung function. Cellular senescence markers are detectable within IPF lung tissue and senescent cell deletion rejuvenates pulmonary health in aged mice. Whether and how senescent cells regulate IPF or if their removal may be an ef...

Alternative Titles

Full title

Cellular senescence mediates fibrotic pulmonary disease

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Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_24b84bad3904485caad4533a2d6fd946

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_24b84bad3904485caad4533a2d6fd946

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms14532

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