Repertoire of P-glycoprotein drug transporters in the zoonotic nematode Toxocara canis
Repertoire of P-glycoprotein drug transporters in the zoonotic nematode Toxocara canis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Toxocara canis
has a complex lifecycle including larval stages in the somatic tissue of dogs that tolerate macrocyclic lactones. In this study, we investigated
T. canis
permeability glycoproteins (P-gps, ABCB1) with a putative role in drug tolerance. Motility experiments demonstrated that while ivermectin failed to abrogate larval movement...
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Full title
Repertoire of P-glycoprotein drug transporters in the zoonotic nematode Toxocara canis
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TN_cdi_doaj_primary_oai_doaj_org_article_254f8c72fb9141f59d71ddd1cd2f5388
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_254f8c72fb9141f59d71ddd1cd2f5388
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-31556-1
