Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays f...
Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Contents
There is overwhelming evidence that in vitro three-dimensional tumor cell cultures more accurately reflect the complex in vivo microenvironment than simple two-dimensional cell monolayers, not least with respect to gene expression profiles, signaling pathway activity and drug sensitivity. However, most currently available three-dimensional techniqu...
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Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation
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TN_cdi_doaj_primary_oai_doaj_org_article_259d7d5fdc4148d8a2d017a4e65b10cd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_259d7d5fdc4148d8a2d017a4e65b10cd
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ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/1741-7007-10-29
