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Do iron homeostasis biomarkers mediate the associations of liability to type 2 diabetes and glycemic...

Do iron homeostasis biomarkers mediate the associations of liability to type 2 diabetes and glycemic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_25af89944d7d446bb1770f34cb7ec1fe

Do iron homeostasis biomarkers mediate the associations of liability to type 2 diabetes and glycemic traits in liver steatosis and cirrhosis: a two-step Mendelian randomization study

About this item

Full title

Do iron homeostasis biomarkers mediate the associations of liability to type 2 diabetes and glycemic traits in liver steatosis and cirrhosis: a two-step Mendelian randomization study

Publisher

England: BioMed Central Ltd

Journal title

BMC medicine, 2024-06, Vol.22 (1), p.270-13, Article 270

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Previous studies, including Mendelian randomization (MR), have demonstrated type 2 diabetes (T2D) and glycemic traits are associated with increased risk of metabolic dysfunction-associated steatotic liver disease (MASLD). However, few studies have explored the underlying pathway, such as the role of iron homeostasis.
We used a two-step MR approa...

Alternative Titles

Full title

Do iron homeostasis biomarkers mediate the associations of liability to type 2 diabetes and glycemic traits in liver steatosis and cirrhosis: a two-step Mendelian randomization study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_25af89944d7d446bb1770f34cb7ec1fe

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_25af89944d7d446bb1770f34cb7ec1fe

Other Identifiers

ISSN

1741-7015

E-ISSN

1741-7015

DOI

10.1186/s12916-024-03486-w

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