Targeting n-myristoyltransferases promotes a pan-Mammarenavirus inhibition through the degradation o...
Targeting n-myristoyltransferases promotes a pan-Mammarenavirus inhibition through the degradation of the Z matrix protein
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Several Old World and New World
Mammarenavirus
are responsible for hemorrhagic fever in humans. These enveloped viruses have a bi-segmented ambisense RNA genome that encodes four proteins. All
Mammarenavirus
identified to date share a common dependency on myristoylation: the addition of the C14 myristic acid on the N-terminal G2 residue...
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Full title
Targeting n-myristoyltransferases promotes a pan-Mammarenavirus inhibition through the degradation of the Z matrix protein
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TN_cdi_doaj_primary_oai_doaj_org_article_25d31a933533497b92cc285f9433ec89
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_25d31a933533497b92cc285f9433ec89
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1012715