An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive b...
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer
About this item
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Author / Creator
Faculty of Medicine , Medicinska fakulteten , Övriga starka forskningsmiljöer , Other Strong Research Environments , Urologi - blåscancer, Malmö , LUCC: Lund University Cancer Centre , Urology - urothelial cancer, Malmö , Institutionen för kliniska vetenskaper, Lund , Section I , Urothelial Cancer Genomics , Lunds universitet , Sektion I , Department of Clinical Sciences, Lund , Genomiska analyser av urinblåscancer , Profilområden och andra starka forskningsmiljöer , Lund University , Urothelial cancer , Department of Translational Medicine , Profile areas and other strong research environments , LUCC: Lunds universitets cancercentrum , Urinblåsecancer , Institutionen för translationell medicin , Lindskrog, Sia Viborg , Prip, Frederik , Lamy, Philippe , Taber, Ann , Groeneveld, Clarice S. , Birkenkamp-Demtröder, Karin , Jensen, Jørgen Bjerggaard , Strandgaard, Trine , Nordentoft, Iver , Christensen, Emil , Sokac, Mateo , Birkbak, Nicolai J. , Maretty, Lasse , Hermann, Gregers G. , Petersen, Astrid C. , Weyerer, Veronika , Grimm, Marc-Oliver , Horstmann, Marcus , Sjödahl, Gottfrid , Höglund, Mattias , Steiniche, Torben , Mogensen, Karin , de Reyniès, Aurélien , Nawroth, Roman , Jordan, Brian , Lin, Xiaoqi , Dragicevic, Dejan , Ward, Douglas G. , Goel, Anshita , Hurst, Carolyn D. , Raman, Jay D. , Warrick, Joshua I. , Segersten, Ulrika , Sikic, Danijel , van Kessel, Kim E. M. , Maurer, Tobias , Meeks, Joshua J. , DeGraff, David J. , Bryan, Richard T. , Knowles, Margaret A. , Simic, Tatjana , Hartmann, Arndt , Zwarthoff, Ellen C. , Malmström, Per-Uno , Malats, Núria , Real, Francisco X. and Dyrskjøt, Lars
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The molecular landscape in non-muscle-invasive bladder cancer (NMIBC) is characterized by large biological heterogeneity with variable clinical outcomes. Here, we perform an integrative multi-omics analysis of patients diagnosed with NMIBC (
n
= 834). Transcriptomic analysis identifies four classes (1, 2a, 2b and 3) reflecting tumor biology...
Alternative Titles
Full title
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer
Authors, Artists and Contributors
Author / Creator
Medicinska fakulteten
Övriga starka forskningsmiljöer
Other Strong Research Environments
Urologi - blåscancer, Malmö
LUCC: Lund University Cancer Centre
Urology - urothelial cancer, Malmö
Institutionen för kliniska vetenskaper, Lund
Section I
Urothelial Cancer Genomics
Lunds universitet
Sektion I
Department of Clinical Sciences, Lund
Genomiska analyser av urinblåscancer
Profilområden och andra starka forskningsmiljöer
Lund University
Urothelial cancer
Department of Translational Medicine
Profile areas and other strong research environments
LUCC: Lunds universitets cancercentrum
Urinblåsecancer
Institutionen för translationell medicin
Lindskrog, Sia Viborg
Prip, Frederik
Lamy, Philippe
Taber, Ann
Groeneveld, Clarice S.
Birkenkamp-Demtröder, Karin
Jensen, Jørgen Bjerggaard
Strandgaard, Trine
Nordentoft, Iver
Christensen, Emil
Sokac, Mateo
Birkbak, Nicolai J.
Maretty, Lasse
Hermann, Gregers G.
Petersen, Astrid C.
Weyerer, Veronika
Grimm, Marc-Oliver
Horstmann, Marcus
Sjödahl, Gottfrid
Höglund, Mattias
Steiniche, Torben
Mogensen, Karin
de Reyniès, Aurélien
Nawroth, Roman
Jordan, Brian
Lin, Xiaoqi
Dragicevic, Dejan
Ward, Douglas G.
Goel, Anshita
Hurst, Carolyn D.
Raman, Jay D.
Warrick, Joshua I.
Segersten, Ulrika
Sikic, Danijel
van Kessel, Kim E. M.
Maurer, Tobias
Meeks, Joshua J.
DeGraff, David J.
Bryan, Richard T.
Knowles, Margaret A.
Simic, Tatjana
Hartmann, Arndt
Zwarthoff, Ellen C.
Malmström, Per-Uno
Malats, Núria
Real, Francisco X.
Dyrskjøt, Lars
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_25de5d15c38f4468b633c9e4bdca4e8d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_25de5d15c38f4468b633c9e4bdca4e8d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-22465-w
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