aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability
aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability
About this item
Full title
Author / Creator
Riddell, Meghan , Nakayama, Akiko , Hikita, Takao , Mirzapourshafiyi, Fatemeh , Kawamura, Takuji , Pasha, Ayesha , Li, Mengnan , Masuzawa, Mikio , Looso, Mario , Steinbacher, Tim , Ebnet, Klaus , Potente, Michael , Hirose, Tomonori , Ohno, Shigeo , Fleming, Ingrid , Gattenlöhner, Stefan , Aung, Phyu P. , Phung, Thuy , Yamasaki, Osamu , Yanagi, Teruki , Umemura, Hiroshi and Nakayama, Masanori
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Strict regulation of proliferation is vital for development, whereas unregulated cell proliferation is a fundamental characteristic of cancer. The polarity protein atypical protein kinase C lambda/iota (aPKCλ) is associated with cell proliferation through unknown mechanisms. In endothelial cells, suppression of aPKCλ impairs proliferation despite h...
Alternative Titles
Full title
aPKC controls endothelial growth by modulating c-Myc via FoxO1 DNA-binding ability
Authors, Artists and Contributors
Author / Creator
Nakayama, Akiko
Hikita, Takao
Mirzapourshafiyi, Fatemeh
Kawamura, Takuji
Pasha, Ayesha
Li, Mengnan
Masuzawa, Mikio
Looso, Mario
Steinbacher, Tim
Ebnet, Klaus
Potente, Michael
Hirose, Tomonori
Ohno, Shigeo
Fleming, Ingrid
Gattenlöhner, Stefan
Aung, Phyu P.
Phung, Thuy
Yamasaki, Osamu
Yanagi, Teruki
Umemura, Hiroshi
Nakayama, Masanori
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_262aa7beda84463ca8dfda4862f93e83
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_262aa7beda84463ca8dfda4862f93e83
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07739-0
