Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Deriv...
Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing
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Switzerland: Frontiers Research Foundation
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Language
English
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Switzerland: Frontiers Research Foundation
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Aβ peptides, the major components of Alzheimer's disease (AD) amyloid deposits, are released following sequential cleavages by secretases of its precursor named the amyloid precursor protein (APP). In addition to secretases, degradation pathways, in particular the endosomal/lysosomal and proteasomal systems have been reported to contribute to APP p...
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Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing
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TN_cdi_doaj_primary_oai_doaj_org_article_2633ffaf0c1f45a6a5fa8fc69f8a5625
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2633ffaf0c1f45a6a5fa8fc69f8a5625
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2018.00435
