Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy
Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Resistant tumours are thought to arise from the action of Darwinian selection on genetically heterogenous cancer cell populations. However, simple clonal selection is inadequate to describe the late relapses often characterising luminal breast cancers treated with endocrine therapy (ET), suggesting a more complex interplay between genetic and non-g...
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Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy
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TN_cdi_doaj_primary_oai_doaj_org_article_266ee5cecff04b52b1a25a258b6d6db4
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_266ee5cecff04b52b1a25a258b6d6db4
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-11721-9
