Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell...
Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Oligodendrocyte progenitor cells (OPC) undergo asymmetric cell division (ACD) to generate one OPC and one differentiating oligodendrocyte (OL) progeny. Loss of pro-mitotic proteoglycan and OPC marker NG2 in the OL progeny is the earliest immunophenotypic change of unknown mechanism that indicates differentiation commitment. Here, we report that exp...
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Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis
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TN_cdi_doaj_primary_oai_doaj_org_article_26828c1df785418aa023dd61fa643620
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_26828c1df785418aa023dd61fa643620
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-05099-3
