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A Study on Repositioning Nalidixic Acid via Lanthanide Complexation: Synthesis, Characterization, Cy...

A Study on Repositioning Nalidixic Acid via Lanthanide Complexation: Synthesis, Characterization, Cy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2690ca2fe5dc477f90f6fe6cee8c5042

A Study on Repositioning Nalidixic Acid via Lanthanide Complexation: Synthesis, Characterization, Cytotoxicity and DNA/Protein Binding Studies

About this item

Full title

A Study on Repositioning Nalidixic Acid via Lanthanide Complexation: Synthesis, Characterization, Cytotoxicity and DNA/Protein Binding Studies

Publisher

Basel: MDPI AG

Journal title

Pharmaceuticals (Basel, Switzerland), 2022-08, Vol.15 (8), p.1010

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

“Drug repositioning” is a modern strategy used to uncover new applications for out-of-date drugs. In this context, nalidixic acid, the first member of the quinolone class with limited use today, has been selected to obtain nine new metal complexes with lanthanide cations (La3+, Sm3+, Eu3+, Gd3+, Tb3+); the experimental data suggest that the quinolo...

Alternative Titles

Full title

A Study on Repositioning Nalidixic Acid via Lanthanide Complexation: Synthesis, Characterization, Cytotoxicity and DNA/Protein Binding Studies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2690ca2fe5dc477f90f6fe6cee8c5042

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2690ca2fe5dc477f90f6fe6cee8c5042

Other Identifiers

ISSN

1424-8247

E-ISSN

1424-8247

DOI

10.3390/ph15081010

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