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Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer

Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_26bc168fc37e4a74ac05932309583845

Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer

About this item

Full title

Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2023-08, Vol.15 (8), p.e17248-n/a

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Endocrine therapies targeting estrogen signaling, such as tamoxifen, have significantly improved management of estrogen receptor alpha (ERα)‐positive breast cancers. However, their efficacy is limited by intrinsic and acquired resistance to treatment, and there is currently no predictive marker of response to these anti‐estrogens to guide treatment...

Alternative Titles

Full title

Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_26bc168fc37e4a74ac05932309583845

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_26bc168fc37e4a74ac05932309583845

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.202217248

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