Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer
Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Endocrine therapies targeting estrogen signaling, such as tamoxifen, have significantly improved management of estrogen receptor alpha (ERα)‐positive breast cancers. However, their efficacy is limited by intrinsic and acquired resistance to treatment, and there is currently no predictive marker of response to these anti‐estrogens to guide treatment...
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Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_26bc168fc37e4a74ac05932309583845
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_26bc168fc37e4a74ac05932309583845
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.202217248