ISG15 deficiency and increased viral resistance in humans but not mice
ISG15 deficiency and increased viral resistance in humans but not mice
About this item
Full title
Author / Creator
Speer, Scott D. , Li, Zhi , Buta, Sofija , Payelle-Brogard, Béatrice , Qian, Li , Vigant, Frederic , Rubino, Erminia , Gardner, Thomas J. , Wedeking, Tim , Hermann, Mark , Duehr, James , Sanal, Ozden , Tezcan, Ilhan , Mansouri, Nahal , Tabarsi, Payam , Mansouri, Davood , Francois-Newton, Véronique , Daussy, Coralie F. , Rodriguez, Marisela R. , Lenschow, Deborah J. , Freiberg, Alexander N. , Tortorella, Domenico , Piehler, Jacob , Lee, Benhur , García-Sastre, Adolfo , Pellegrini, Sandra and Bogunovic, Dusan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
ISG15 is an interferon (IFN)-α/β-induced ubiquitin-like protein. It exists as a free molecule, intracellularly and extracellularly, and conjugated to target proteins. Studies in mice have demonstrated a role for Isg15 in antiviral immunity. By contrast, human ISG15 was shown to have critical immune functions, but not in antiviral immunity. Namely,...
Alternative Titles
Full title
ISG15 deficiency and increased viral resistance in humans but not mice
Authors, Artists and Contributors
Author / Creator
Li, Zhi
Buta, Sofija
Payelle-Brogard, Béatrice
Qian, Li
Vigant, Frederic
Rubino, Erminia
Gardner, Thomas J.
Wedeking, Tim
Hermann, Mark
Duehr, James
Sanal, Ozden
Tezcan, Ilhan
Mansouri, Nahal
Tabarsi, Payam
Mansouri, Davood
Francois-Newton, Véronique
Daussy, Coralie F.
Rodriguez, Marisela R.
Lenschow, Deborah J.
Freiberg, Alexander N.
Tortorella, Domenico
Piehler, Jacob
Lee, Benhur
García-Sastre, Adolfo
Pellegrini, Sandra
Bogunovic, Dusan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_26d5278e9a6e4fe9b0df50d459031fb1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_26d5278e9a6e4fe9b0df50d459031fb1
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms11496
