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Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal devel...

Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal devel...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_26ec0393d8414ff985171a47ea4a1728

Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development

About this item

Full title

Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-04, Vol.11 (1), p.1674-21, Article 1674

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Neurodevelopment requires precise regulation of gene expression, including post-transcriptional regulatory events such as alternative splicing and mRNA translation. However, translational regulation of specific isoforms during neurodevelopment and the mechanisms behind it remain unknown. Using RNA-seq analysis of mouse neocortical polysomes, here w...

Alternative Titles

Full title

Translational derepression of Elavl4 isoforms at their alternative 5′ UTRs determines neuronal development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_26ec0393d8414ff985171a47ea4a1728

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_26ec0393d8414ff985171a47ea4a1728

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-15412-8

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