The quest for balance between capturing data and model complexity: A quantitative clinical pharmacol...
The quest for balance between capturing data and model complexity: A quantitative clinical pharmacology approach applied to monoclonal antibodies
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United States: John Wiley & Sons, Inc
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Language
English
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Publisher
United States: John Wiley & Sons, Inc
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The main objective of this tutorial is to provide the readers with a roadmap of how to establish increasingly complex target‐mediated drug disposition (TMDD) models for monoclonal antibodies. To this end, we built mathematical models, each with a detailed visualization, starting from the basic TMDD model by Mager and Jusko to the well‐established,...
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Full title
The quest for balance between capturing data and model complexity: A quantitative clinical pharmacology approach applied to monoclonal antibodies
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TN_cdi_doaj_primary_oai_doaj_org_article_26f7499bfef749dda8f7599767d5d989
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_26f7499bfef749dda8f7599767d5d989
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ISSN
2163-8306
E-ISSN
2163-8306
DOI
10.1002/psp4.12927
