BDNF val66met Polymorphism Impairs Hippocampal Long-Term Depression by Down-Regulation of 5-HT3 Rece...
BDNF val66met Polymorphism Impairs Hippocampal Long-Term Depression by Down-Regulation of 5-HT3 Receptors
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Author / Creator
Hao, Rui , Qi, Yu , Hou, Dong-Ni , Ji, Yuan-Yuan , Zheng, Chun-Yan , Li, Chu-Yu , Yung, Wing-Ho , Lu, Bai and Huang, Ying
Publisher
Switzerland: Frontiers Research Foundation
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Language
English
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Publisher
Switzerland: Frontiers Research Foundation
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Contents
Brain-derived neurotrophic factor (BDNF) is a key regulator of neuronal plasticity and cognitive functions. BDNF val66met polymorphism, a human single-nucleotide polymorphism (SNP) in the pro-domain of BDNF gene, is associated with deficits in activity-dependent BDNF secretion and hippocampus-dependent memory. However, the underlying mechanism rema...
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Full title
BDNF val66met Polymorphism Impairs Hippocampal Long-Term Depression by Down-Regulation of 5-HT3 Receptors
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TN_cdi_doaj_primary_oai_doaj_org_article_273e310ac7164f9ea346282659e94099
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_273e310ac7164f9ea346282659e94099
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ISSN
1662-5102
E-ISSN
1662-5102
DOI
10.3389/fncel.2017.00306
