Splicing repression allows the gradual emergence of new Alu-exons in primate evolution
Splicing repression allows the gradual emergence of new Alu-exons in primate evolution
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England: eLife Science Publications, Ltd
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English
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Publisher
England: eLife Science Publications, Ltd
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Alu elements are retrotransposons that frequently form new exons during primate evolution. Here, we assess the interplay of splicing repression by hnRNPC and nonsense-mediated mRNA decay (NMD) in the quality control and evolution of new Alu-exons. We identify 3100 new Alu-exons and show that NMD more efficiently recognises transcripts with Alu-exon...
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Splicing repression allows the gradual emergence of new Alu-exons in primate evolution
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TN_cdi_doaj_primary_oai_doaj_org_article_2742a90fdd0c4b8cacf59ddf90269aa9
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2742a90fdd0c4b8cacf59ddf90269aa9
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.19545
