Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta
Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta
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England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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Cryo-EM has revealed the structures of many challenging yet exciting macromolecular assemblies at near-atomic resolution (3–4.5Å), providing biological phenomena with molecular descriptions. However, at these resolutions, accurately positioning individual atoms remains challenging and error-prone. Manually refining thousands of amino acids – typica...
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Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta
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TN_cdi_doaj_primary_oai_doaj_org_article_274c901936dd4245a3d98b6ea92319b5
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_274c901936dd4245a3d98b6ea92319b5
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.17219
