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Cooperation between a hierarchical set of recruitment sites targets the X chromosome for dosage comp...

Cooperation between a hierarchical set of recruitment sites targets the X chromosome for dosage comp...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_276b4d3270344bc9a64b3889aa8b15b1

Cooperation between a hierarchical set of recruitment sites targets the X chromosome for dosage compensation

About this item

Full title

Cooperation between a hierarchical set of recruitment sites targets the X chromosome for dosage compensation

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2017-05, Vol.6

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

In many organisms, it remains unclear how X chromosomes are specified for dosage compensation, since DNA sequence motifs shown to be important for dosage compensation complex (DCC) recruitment are themselves not X-specific. Here, we addressed this problem in C. elegans. We found that the DCC recruiter, SDC-2, is required to maintain open chromatin...

Alternative Titles

Full title

Cooperation between a hierarchical set of recruitment sites targets the X chromosome for dosage compensation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_276b4d3270344bc9a64b3889aa8b15b1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_276b4d3270344bc9a64b3889aa8b15b1

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.23645

How to access this item