Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasi...
Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The majority of breast cancer models for drug discovery are based on orthotopic or subcutaneous tumours. Therapeutic responses of metastases, especially microscopic metastases, are likely to differ from these tumours due to distinct cancer-microenvironment crosstalk in distant organs. Here, to recapitulate such differences, we established an
ex...
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Full title
Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies
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TN_cdi_doaj_primary_oai_doaj_org_article_277b6262d22942908dfbeb83711138c3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_277b6262d22942908dfbeb83711138c3
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms15045
