Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based mic...
Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Interactions between adipose tissue, liver and immune system are at the center of metabolic dysfunction-associated steatotic liver disease and type 2 diabetes. To address the need for an accurate in vitro model, we establish an interconnected microphysiological system (MPS) containing white adipocytes, hepatocytes and proinflammatory macrophages de...
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Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system
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TN_cdi_doaj_primary_oai_doaj_org_article_278065363b2c41c582d81e0c6481a1ce
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_278065363b2c41c582d81e0c6481a1ce
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-52258-w
