Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells
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Author / Creator
Candas-Green, Demet , Xie, Bowen , Huang, Jie , Fan, Ming , Wang, Aijun , Menaa, Cheikh , Zhang, Yanhong , Zhang, Lu , Jing, Di , Azghadi, Soheila , Zhou, Weibing , Liu, Lin , Jiang, Nian , Li, Tao , Gao, Tianyi , Sweeney, Colleen , Shen, Rulong , Lin, Tzu-yin , Pan, Chong-xian , Ozpiskin, Omer M. , Woloschak, Gayle , Grdina, David J. , Vaughan, Andrew T. , Wang, Ji Ming , Xia, Shuli , Monjazeb, Arta M. , Murphy, William J. , Sun, Lun-Quan , Chen, Hong-Wu , Lam, Kit S. , Weichselbaum, Ralph R. and Li, Jian Jian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Although the efficacy of cancer radiotherapy (RT) can be enhanced by targeted immunotherapy, the immunosuppressive factors induced by radiation on tumor cells remain to be identified. Here, we report that CD47-mediated anti-phagocytosis is concurrently upregulated with HER2 in radioresistant breast cancer (BC) cells and RT-treated mouse syngeneic B...
Alternative Titles
Full title
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells
Authors, Artists and Contributors
Author / Creator
Xie, Bowen
Huang, Jie
Fan, Ming
Wang, Aijun
Menaa, Cheikh
Zhang, Yanhong
Zhang, Lu
Jing, Di
Azghadi, Soheila
Zhou, Weibing
Liu, Lin
Jiang, Nian
Li, Tao
Gao, Tianyi
Sweeney, Colleen
Shen, Rulong
Lin, Tzu-yin
Pan, Chong-xian
Ozpiskin, Omer M.
Woloschak, Gayle
Grdina, David J.
Vaughan, Andrew T.
Wang, Ji Ming
Xia, Shuli
Monjazeb, Arta M.
Murphy, William J.
Sun, Lun-Quan
Chen, Hong-Wu
Lam, Kit S.
Weichselbaum, Ralph R.
Li, Jian Jian
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_278b23d810204e89b5b3f18e5d760fef
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_278b23d810204e89b5b3f18e5d760fef
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-18245-7
