Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respirator...
Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection
About this item
Full title
Author / Creator
Koenecke, Allison , Powell, Michael , Xiong, Ruoxuan , Shen, Zhu , Fischer, Nicole , Huq, Sakibul , Khalafallah, Adham M , Trevisan, Marco , Sparen, Pär , Carrero, Juan J , Nishimura, Akihiko , Caffo, Brian , Stuart, Elizabeth A , Bai, Renyuan , Staedtke, Verena , Thomas, David L , Papadopoulos, Nickolas , Kinzler, Ken W , Vogelstein, Bert , Zhou, Shibin , Bettegowda, Chetan , Konig, Maximilian F , Mensh, Brett D , Vogelstein, Joshua T and Athey, Susan
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Sciences Publications Ltd
Subjects
More information
Scope and Contents
Contents
In severe viral pneumonia, including Coronavirus disease 2019 (COVID-19), the viral replication phase is often followed by hyperinflammation, which can lead to acute respiratory distress syndrome, multi-organ failure, and death. We previously demonstrated that alpha-1 adrenergic receptor (⍺
1
-AR) antagonists can prevent hyperinflammation and...
Alternative Titles
Full title
Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection
Authors, Artists and Contributors
Author / Creator
Powell, Michael
Xiong, Ruoxuan
Shen, Zhu
Fischer, Nicole
Huq, Sakibul
Khalafallah, Adham M
Trevisan, Marco
Sparen, Pär
Carrero, Juan J
Nishimura, Akihiko
Caffo, Brian
Stuart, Elizabeth A
Bai, Renyuan
Staedtke, Verena
Thomas, David L
Papadopoulos, Nickolas
Kinzler, Ken W
Vogelstein, Bert
Zhou, Shibin
Bettegowda, Chetan
Konig, Maximilian F
Mensh, Brett D
Vogelstein, Joshua T
Athey, Susan
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_27cc1efbc7b74373ace05076206c199b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_27cc1efbc7b74373ace05076206c199b
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.61700
