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Novel Human Podocyte Cell Model Carrying G2/G2 APOL1 High-Risk Genotype

Novel Human Podocyte Cell Model Carrying G2/G2 APOL1 High-Risk Genotype

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_27dfaf9c07444f8f8aed4e5aaec8babd

Novel Human Podocyte Cell Model Carrying G2/G2 APOL1 High-Risk Genotype

About this item

Full title

Novel Human Podocyte Cell Model Carrying G2/G2 APOL1 High-Risk Genotype

Publisher

Basel: MDPI AG

Journal title

Cells (Basel, Switzerland), 2021-07, Vol.10 (8), p.1914

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

Apolipoprotein L1 (APOL1) high-risk genotypes (HRG), G1 and G2, increase the risk of various non-diabetic kidney diseases in the African population. To date, the precise mechanisms by which APOL1 risk variants induce injury on podocytes and other kidney cells remain unclear. Trying to unravel these mechanisms, most studies have used animal or cell...

Alternative Titles

Full title

Novel Human Podocyte Cell Model Carrying G2/G2 APOL1 High-Risk Genotype

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_27dfaf9c07444f8f8aed4e5aaec8babd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_27dfaf9c07444f8f8aed4e5aaec8babd

Other Identifiers

ISSN

2073-4409

E-ISSN

2073-4409

DOI

10.3390/cells10081914

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