Mitochondria Clumping vs. Mitochondria Fusion in CMT2A Diseases
Mitochondria Clumping vs. Mitochondria Fusion in CMT2A Diseases
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Phenotypic variations in Charcot-Marie-Tooth disease type 2A (CMT2A) result from the many mutations in the mitochondrial fusion protein, mitofusin 2 (MFN2). While the GTPase domain mutations of MFN2 lack the ability to hydrolyze GTP and complete mitochondrial fusion, the mechanism of dysfunction in HR1 domain mutations has yet to be explored. Using...
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Mitochondria Clumping vs. Mitochondria Fusion in CMT2A Diseases
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TN_cdi_doaj_primary_oai_doaj_org_article_27e58eb8005141a4b94788399de997d6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_27e58eb8005141a4b94788399de997d6
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ISSN
2075-1729
E-ISSN
2075-1729
DOI
10.3390/life12122110
