Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveo...
Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Caveolae are spherically shaped nanodomains of the plasma membrane, generated by cooperative assembly of caveolin and cavin proteins. Cavins are cytosolic peripheral membrane proteins with negatively charged intrinsically disordered regions that flank positively charged α-helical regions. Here, we show that the three disordered domains of Cavin1 ar...
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Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
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TN_cdi_doaj_primary_oai_doaj_org_article_2807bb40181f4244bd067fd1cb562ab3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2807bb40181f4244bd067fd1cb562ab3
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-21035-4
