A novel function for α-synuclein as a regulator of NCK2 in olfactory bulb: implications for its role...
A novel function for α-synuclein as a regulator of NCK2 in olfactory bulb: implications for its role in olfaction
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Author / Creator
Ren, Jing , Wu, Chao , Zeng, Mengxia , Qu, Mingqin , Gao, Ge , Chen, Ning , Yue, Jingjing , Jiang, Yuwen , Zhao, Tongfei , Xiang, Na , Meng, Fangang and Lu, Ling-ling
Publisher
England: BMC
Journal title
Language
English
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Publisher
England: BMC
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Contents
To investigate physiological function of α-synuclein is important for understanding its pathophysiological mechanism in synucleinopathies including Parkinson’s disease. Employing knockout mice, we found that Snac/α-synuclein deletion induced aberrant projection of olfactory sensory neurons and hyposmia. We identified 9 axon guidance associated diff...
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Full title
A novel function for α-synuclein as a regulator of NCK2 in olfactory bulb: implications for its role in olfaction
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_280939f9b7474a71acff6b680305c693
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_280939f9b7474a71acff6b680305c693
Other Identifiers
ISSN
2045-3701
E-ISSN
2045-3701
DOI
10.1186/s13578-024-01313-6
