Log in to save to my catalogue
Log in to save to my catalogue

SKI‐G‐801, an AXL kinase inhibitor, blocks metastasis through inducing anti‐tumor immune responses a...

| Ask | Become a Library member

SKI‐G‐801, an AXL kinase inhibitor, blocks metastasis through inducing anti‐tumor immune responses a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2810ccf729dc4cf68402dc5c21aa1ea6

SKI‐G‐801, an AXL kinase inhibitor, blocks metastasis through inducing anti‐tumor immune responses and potentiates anti‐PD‐1 therapy in mouse cancer models

About this item

Full title

SKI‐G‐801, an AXL kinase inhibitor, blocks metastasis through inducing anti‐tumor immune responses and potentiates anti‐PD‐1 therapy in mouse cancer models

Author / Creator

Synn, Chun‐Bong , Kim, Sung Eun , Lee, Hee Kyu , Kim, Min‐Hwan , Kim, Jae Hwan , Lee, Ji Min , Jo, Ha Ni , Lee, Wongeun , Kim, Dong Kwon , Byeon, Youngseon , Kim, Young Seob , Yun, Mi Ran , Park, Chae‐Won , Yun, Jiyeon , Lim, Sangbin , Heo, Seong Gu , Yang, San‐Duk , Lee, Eun Ji , Lee, Seul , Choi, Hunmi , Lee, You Won , Cho, Jae Seok , Kim, Do Hee , Park, Sungho , Kim, Jung‐Ho , Choi, Yewon , Lee, Sung Sook , Ahn, Beung‐Chul , Kim, Chang Gon , Lim, Sun Min , Hong, Min Hee , Kim, Hye Ryun , Pyo, Kyoung‐Ho and Cho, Byoung Chul

Publisher

Australia: John Wiley & Sons, Inc

Journal title

Clinical & Translational Immunology, 2022, Vol.11 (1), p.e1364-n/a

Language

English

Formats

Articles

Publication information

Publisher

Australia: John Wiley & Sons, Inc

Subjects

More information

Scope and Contents

Contents

Objectives
AXL‐mediated activation of aberrant tyrosine kinase drives various oncogenic processes and facilitates an immunosuppressive microenvironment. We evaluated the anti‐tumor and anti‐metastatic activities of SKI‐G‐801, a small‐molecule inhibitor of AXL, alone and in combination with anti‐PD‐1 therapy.
Methods
In vitro pAXL inhibitio...

Alternative Titles

Full title

SKI‐G‐801, an AXL kinase inhibitor, blocks metastasis through inducing anti‐tumor immune responses and potentiates anti‐PD‐1 therapy in mouse cancer models

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_2810ccf729dc4cf68402dc5c21aa1ea6

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2810ccf729dc4cf68402dc5c21aa1ea6

Other Identifiers

ISSN

2050-0068

E-ISSN

2050-0068

DOI

10.1002/cti2.1364

How to access this item

Log in as a Library member

Full text available

About resource

View in old catalogue

Connecting people and collections