PEAR, a flexible fluorescent reporter for the identification and enrichment of successfully prime ed...
PEAR, a flexible fluorescent reporter for the identification and enrichment of successfully prime edited cells
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Publisher
England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Prime editing is a recently developed CRISPR/Cas9 based gene engineering tool that allows the introduction of short insertions, deletions, and substitutions into the genome. However, the efficiency of prime editing, which typically achieves editing rates of around 10%-30%, has not matched its versatility. Here, we introduce the prime editor activit...
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Full title
PEAR, a flexible fluorescent reporter for the identification and enrichment of successfully prime edited cells
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TN_cdi_doaj_primary_oai_doaj_org_article_2832519c90ae4f6380f0a4179e621568
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2832519c90ae4f6380f0a4179e621568
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.69504
