Identification of Mtb GlmU Uridyltransferase Domain Inhibitors by Ligand-Based and Structure-Based D...
Identification of Mtb GlmU Uridyltransferase Domain Inhibitors by Ligand-Based and Structure-Based Drug Design Approaches
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Targeting enzymes that play a role in the biosynthesis of the bacterial cell wall has long been a strategy for antibacterial discovery. In particular, the cell wall of Mycobacterium tuberculosis (Mtb) is a complex of three layers, one of which is Peptidoglycan, an essential component providing rigidity and strength. UDP-GlcNAc, a precursor for the...
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Identification of Mtb GlmU Uridyltransferase Domain Inhibitors by Ligand-Based and Structure-Based Drug Design Approaches
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TN_cdi_doaj_primary_oai_doaj_org_article_28374e2f6f1a4d6a8d4a179d51b5585a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28374e2f6f1a4d6a8d4a179d51b5585a
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules27092805
