Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma
Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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The intrinsic drivers of migration in glioblastoma (GBM) are poorly understood. To better capture the native molecular imprint of GBM and its developmental context, here we isolate human stem cell populations from GBM (GSC) and germinal matrix tissues and map their chromatin accessibility via ATAC-seq. We uncover two distinct regulatory GSC signatu...
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Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma
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TN_cdi_doaj_primary_oai_doaj_org_article_2866f4fd16df494d96b315c2101ad08d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2866f4fd16df494d96b315c2101ad08d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-06258-2
