Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progeni...
Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors
About this item
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Author / Creator
Mavrommatis, Lampros , Jeong, Hyun-Woo , Kindler, Urs , Gomez-Giro, Gemma , Kienitz, Marie-Cecile , Stehling, Martin , Psathaki, Olympia E , Zeuschner, Dagmar , Bixel, M Gabriele , Han, Dong , Morosan-Puopolo, Gabriela , Gerovska, Daniela , Yang, Ji Hun , Kim, Jeong Beom , Arauzo-Bravo, Marcos J , Schwamborn, Jens C , Hahn, Stephan A , Adams, Ralf H , Schöler, Hans R , Vorgerd, Matthias , Brand-Saberi, Beate and Zaehres, Holm
Publisher
Cambridge: eLife Science Publications, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Cambridge: eLife Science Publications, Ltd
Subjects
More information
Scope and Contents
Contents
In vitro culture systems that structurally model human myogenesis and promote PAX7+ myogenic progenitor maturation have not been established. Here we report that human skeletal muscle organoids can be differentiated from induced pluripotent stem cell lines to contain paraxial mesoderm and neuromesodermal progenitors and develop into organized struc...
Alternative Titles
Full title
Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors
Authors, Artists and Contributors
Author / Creator
Jeong, Hyun-Woo
Kindler, Urs
Gomez-Giro, Gemma
Kienitz, Marie-Cecile
Stehling, Martin
Psathaki, Olympia E
Zeuschner, Dagmar
Bixel, M Gabriele
Han, Dong
Morosan-Puopolo, Gabriela
Gerovska, Daniela
Yang, Ji Hun
Kim, Jeong Beom
Arauzo-Bravo, Marcos J
Schwamborn, Jens C
Hahn, Stephan A
Adams, Ralf H
Schöler, Hans R
Vorgerd, Matthias
Brand-Saberi, Beate
Zaehres, Holm
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_2882c4b7b3864986853c1bc24996070e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2882c4b7b3864986853c1bc24996070e
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.87081
