Anti-cancer characteristics and ototoxicity of platinum(II) amine complexes with only one leaving li...
Anti-cancer characteristics and ototoxicity of platinum(II) amine complexes with only one leaving ligand
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Unlike cisplatin, which forms bifunctional DNA adducts, monofunctional platinum(II) complexes bind only one strand of DNA and might target cancer without causing auditory side-effects associated with cisplatin treatment. We synthesized the monofunctional triamine-ligated platinum(II) complexes, Pt(diethylenetriamine)Cl, [Pt(dien)Cl]+, and Pt(N,N-di...
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Anti-cancer characteristics and ototoxicity of platinum(II) amine complexes with only one leaving ligand
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TN_cdi_doaj_primary_oai_doaj_org_article_2892b6c685c043dca707f59109576672
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_2892b6c685c043dca707f59109576672
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0192505
