Calaxin stabilizes the docking of outer arm dyneins onto ciliary doublet microtubule in vertebrates
Calaxin stabilizes the docking of outer arm dyneins onto ciliary doublet microtubule in vertebrates
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England: eLife Sciences Publications, Ltd
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English
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England: eLife Sciences Publications, Ltd
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Outer arm dynein (OAD) is the main force generator of ciliary beating. Although OAD loss is the most frequent cause of human primary ciliary dyskinesia, the docking mechanism of OAD onto the ciliary doublet microtubule (DMT) remains elusive in vertebrates. Here, we analyzed the functions of Calaxin/Efcab1 and Armc4, the two of five components of ve...
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Full title
Calaxin stabilizes the docking of outer arm dyneins onto ciliary doublet microtubule in vertebrates
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TN_cdi_doaj_primary_oai_doaj_org_article_28964cccf4534789bf6050ed348ace74
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28964cccf4534789bf6050ed348ace74
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.84860
