The proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty ac...
The proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty acid synthesis
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Author / Creator
Zhao, Wentao , Ouyang, Cong , Zhang, Liang , Wang, Jinyang , Zhang, Jiaojiao , Zhang, Yan , Huang, Chen , Xiao, Qiao , Jiang, Bin , Lin, Furong , Zhang, Cixiong , Zhu, Mingxia , Xie, Changchuan , Huang, Xi , Zhang, Bingchang , Zhao, Wenpeng , He, Jiawei , Chen, Sifang , Liu, Xiyao , Lin, Donghai , Li, Qinxi and Wang, Zhanxiang
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Increased fatty acid synthesis benefits glioblastoma malignancy. However, the coordinated regulation of cytosolic acetyl-CoA production, the exclusive substrate for fatty acid synthesis, remains unclear. Here, we show that proto-oncogene tyrosine kinase c-SRC is activated in glioblastoma and remodels cytosolic acetyl-CoA production for fatty acid s...
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Full title
The proto-oncogene tyrosine kinase c-SRC facilitates glioblastoma progression by remodeling fatty acid synthesis
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TN_cdi_doaj_primary_oai_doaj_org_article_28a3de9cf84e4de19def6999bfe58e5a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28a3de9cf84e4de19def6999bfe58e5a
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-51444-0
