Protein import motor complex reacts to mitochondrial misfolding by reducing protein import and activ...
Protein import motor complex reacts to mitochondrial misfolding by reducing protein import and activating mitophagy
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Mitophagy is essential to maintain mitochondrial function and prevent diseases. It activates upon mitochondria depolarization, which causes PINK1 stabilization on the mitochondrial outer membrane. Strikingly, a number of conditions, including mitochondrial protein misfolding, can induce mitophagy without a loss in membrane potential. The underlying...
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Full title
Protein import motor complex reacts to mitochondrial misfolding by reducing protein import and activating mitophagy
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TN_cdi_doaj_primary_oai_doaj_org_article_28bd4ad93a744efda167cac0232e31a7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28bd4ad93a744efda167cac0232e31a7
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-32564-x
