Iron overload adversely effects bone marrow haematogenesis via SIRT-SOD2-mROS in a process ameliorat...
Iron overload adversely effects bone marrow haematogenesis via SIRT-SOD2-mROS in a process ameliorated by curcumin
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Author / Creator
Zhou, Shujuan , Sun, Lan , Qian, Shanhu , Ma, Yongyong , Ma, Ruye , Dong, Yuqing , Shi, Yifen , Jiang, Songfu , Ye, Haige , Shen, Zhijian , Zhang, Shenghui , Shen, Jianping , Yu, Kang and Wang, Siqian
Publisher
England: BioMed Central
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
Iron overload, which is common in patients with haematological disorders, is known to have a suppressive effect on haematogenesis. However, the mechanism for this effect is still unclear. The antioxidant curcumin has been reported to protect against iron overload-induced bone marrow damage through an as-yet-unknown mechanism.
We established iron...
Alternative Titles
Full title
Iron overload adversely effects bone marrow haematogenesis via SIRT-SOD2-mROS in a process ameliorated by curcumin
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_28c412f7e025470489b85257d6e865c9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28c412f7e025470489b85257d6e865c9
Other Identifiers
ISSN
1425-8153
E-ISSN
1689-1392
DOI
10.1186/s11658-020-00244-7
