Determination of Nemonoxacin in Small Volumes of Rat Plasma and Bile by a Novel HPLC-Fluorescence As...
Determination of Nemonoxacin in Small Volumes of Rat Plasma and Bile by a Novel HPLC-Fluorescence Assay and Its Application to Disposition and Biliary Excretion Kinetics
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New Zealand: Dove Medical Press Limited
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Language
English
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New Zealand: Dove Medical Press Limited
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Nemonoxacin is a novel non-fluorinated quinolone antibiotic for the treatment of community-acquired pneumonia. To investigate the pharmacokinetics (PK) of nemonoxacin, a simple and sensitive high-performance liquid chromatography assay (HPLC) was needed.
An HPLC method with fluorescence (FL) detection was developed for the quantification of nemo...
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Full title
Determination of Nemonoxacin in Small Volumes of Rat Plasma and Bile by a Novel HPLC-Fluorescence Assay and Its Application to Disposition and Biliary Excretion Kinetics
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TN_cdi_doaj_primary_oai_doaj_org_article_28db6c0075dc4e34a30b8a91ca2918bb
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28db6c0075dc4e34a30b8a91ca2918bb
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ISSN
1177-8881
E-ISSN
1177-8881
DOI
10.2147/DDDT.S476173
