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Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28db9dcc2962496aac08fb8a9dcff7e0

Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

About this item

Full title

Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

Publisher

Switzerland: MDPI AG

Journal title

Biomolecules (Basel, Switzerland), 2021-05, Vol.11 (6), p.779

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Although ubiquitination is widely assumed to be the only regulated step in the ubiquitin–proteasome pathway, recent studies have demonstrated several important mechanisms that regulate the activities of the 26S proteasome. Most proteasomes in cells are inactive but, upon binding a ubiquitinated substrate, become activated by a two-step mechanism re...

Alternative Titles

Full title

Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_28db9dcc2962496aac08fb8a9dcff7e0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28db9dcc2962496aac08fb8a9dcff7e0

Other Identifiers

ISSN

2218-273X

E-ISSN

2218-273X

DOI

10.3390/biom11060779

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