Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation
Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Although ubiquitination is widely assumed to be the only regulated step in the ubiquitin–proteasome pathway, recent studies have demonstrated several important mechanisms that regulate the activities of the 26S proteasome. Most proteasomes in cells are inactive but, upon binding a ubiquitinated substrate, become activated by a two-step mechanism re...
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Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation
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TN_cdi_doaj_primary_oai_doaj_org_article_28db9dcc2962496aac08fb8a9dcff7e0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_28db9dcc2962496aac08fb8a9dcff7e0
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ISSN
2218-273X
E-ISSN
2218-273X
DOI
10.3390/biom11060779