Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease
Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease
About this item
Full title
Author / Creator
Melanie Ricke-Hoch , Elisabeth Stelling , Lisa Lasswitz , Antonia P Gunesch , Martina Kasten , Francisco J Zapatero-Belinchón , Graham Brogden , Gisa Gerold , Thomas Pietschmann , Virginie Montiel , Jean-Luc Balligand , Federica Facciotti , Emilio Hirsch , Thomas Gausepohl , Husni Elbahesh , Guus F Rimmelzwaan , Anne Höfer , Mark P Kühnel , Danny Jonigk , Julian Eigendorf , Uwe Tegtbur , Lena Mink , Michaela Scherr , Thomas Illig , Axel Schambach , Tobias J Pfeffer , Andres Hilfiker , Axel Haverich and Denise Hilfiker-Kleiner
Publisher
Public Library of Science (PLoS)
Journal title
Language
English
Formats
Publication information
Publisher
Public Library of Science (PLoS)
More information
Scope and Contents
Contents
The SARS-CoV-2 coronavirus has led to a pandemic with millions of people affected. The present study finds that risk-factors for severe COVID-19 disease courses, i.e. male sex, older age and sedentary life style are associated with higher prostaglandin E2 (PGE2) serum levels in blood samples from unaffected subjects. In COVID-19 patients, PGE2 bloo...
Alternative Titles
Full title
Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease
Authors, Artists and Contributors
Author / Creator
Elisabeth Stelling
Lisa Lasswitz
Antonia P Gunesch
Martina Kasten
Francisco J Zapatero-Belinchón
Graham Brogden
Gisa Gerold
Thomas Pietschmann
Virginie Montiel
Jean-Luc Balligand
Federica Facciotti
Emilio Hirsch
Thomas Gausepohl
Husni Elbahesh
Guus F Rimmelzwaan
Anne Höfer
Mark P Kühnel
Danny Jonigk
Julian Eigendorf
Uwe Tegtbur
Lena Mink
Michaela Scherr
Thomas Illig
Axel Schambach
Tobias J Pfeffer
Andres Hilfiker
Axel Haverich
Denise Hilfiker-Kleiner
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_29020b7734ec4bb5ae0e7a607b498ae0
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29020b7734ec4bb5ae0e7a607b498ae0
Other Identifiers
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0255335
