The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2
The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2
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Author / Creator
Maimaiti, Maihulan , Sakamoto, Shinichi , Sugiura, Masahiro , Kanesaka, Manato , Fujimoto, Ayumi , Matsusaka, Keisuke , Xu, Minhui , Ando, Keisuke , Saito, Shinpei , Wakai, Ken , Imamura, Yusuke , Nakayama, Keiichi , Kanai, Yoshikatsu , Kaneda, Atsushi , Ikehara, Yuzuru , Ikeda, Jun-Ichiro , Anzai, Naohiko and Ichikawa, Tomohiko
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
The 4F2 cell-surface antigen heavy chain (4F2hc) forms a heterodimeric complex with L-type amino acid transporter 1 (LAT1) and transports large neutral essential amino acids. However, in contrast to the traditional role of LAT1 in various cancers, the role of 4F2hc has largely remained unknown. The role of 4F2hc in prostate cancer was studied. Trea...
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Full title
The heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2
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TN_cdi_doaj_primary_oai_doaj_org_article_29192c71cd4c466db76e5d10cfc62d81
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_29192c71cd4c466db76e5d10cfc62d81
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-90748-9
