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USP14 inhibition corrects an in vivo model of impaired mitophagy

USP14 inhibition corrects an in vivo model of impaired mitophagy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_291aa43de92046d2919c57ef5223240c

USP14 inhibition corrects an in vivo model of impaired mitophagy

About this item

Full title

USP14 inhibition corrects an in vivo model of impaired mitophagy

Publisher

London: Nature Publishing Group UK

Journal title

EMBO molecular medicine, 2018-11, Vol.10 (11), p.1-n/a

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mitochondrial autophagy or mitophagy is a key process that allows selective sequestration and degradation of dysfunctional mitochondria to prevent excessive reactive oxygen species, and activation of cell death. Recent studies revealed that ubiquitin–proteasome complex activity and mitochondrial membrane rupture are key steps preceding mitophagy, i...

Alternative Titles

Full title

USP14 inhibition corrects an in vivo model of impaired mitophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_291aa43de92046d2919c57ef5223240c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_291aa43de92046d2919c57ef5223240c

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.201809014

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